The President has the power to appoint and dismiss Permanent Secretaries, etc..
Section 205, Guyana Constitution.
https://www.oas.org/juridico/s...guy_constitution.pdf
Section 205, subsections ( 1 ) & ( 3 )
205. (l) The power to make appointments to the offices to which this article applies and to remove from office persons holding or acting in such offices shall vest in the President.
(2) Before making an appointment under paragraph (1) in favour of any person who holds any public office other than an office to which this article applies, the President shall consult the appropriate Commission.
(3) The offices to which this article applies are the offices of Solicitor General, Permanent Secretary, to the Cabinet, Ambassador, High Commissioner or other principal representative of Guyana in any other country or accredited to any international organisation.
(4) In paragraph (2) of this article “the appropriate Commission” means, in the case of a person who holds an office power to make appointments to which is vested in the President acting in accordance with the advice of the Judicial Service Commission or is vested in that Commission, the Judicial Service Commission, in the case of a person who is a teacher in the public service, the Teaching Service Commission, in the case of a person who holds an office power to make appointments to which is vested in the President acting in accordance with the advice of the Police Service Commission or is vested in that Commission, the Police Service Commission, and in any other case the Public Service Commission.